Mechanisms of tolerance to DNA damaging therapeutic drugs
نویسندگان
چکیده
منابع مشابه
DNA Damaging Drugs
DNA damaging drugs interfere with transcription and reduplication. Affected cells respond with cell cycle arrest or programmed cell death. DNA damaging drugs are mutagenic, teratogenic, and carcinogenic. Adverse effects are exerted on rapidly proliferating cells (skin—hair loss, gastrointestinal tract—nausea and vomiting, bone marrow—anemia causing fatigue/leukopenia causing infections/thromboc...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2001
ISSN: 1460-2180,0143-3334
DOI: 10.1093/carcin/22.12.1931